https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 The neural addiction of cancer https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52966 Wed 28 Feb 2024 16:08:27 AEDT ]]> Central integration of cardiopulmonary autonomic controls https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12889 Wed 24 Jul 2013 22:25:22 AEST ]]> Central nervous μ-opioid and 5-hydroxytryptamine influence on baroreflex evoked coronary vasodilatation in the dog https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12746 Wed 24 Jul 2013 22:24:31 AEST ]]> Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:13672 Wed 11 Apr 2018 16:23:10 AEST ]]> Oxycodone overdose causes naloxone responsive coma and QT prolongation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14505 Wed 11 Apr 2018 15:19:38 AEST ]]> Practice pointer: serotonin syndrome https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14543 Wed 11 Apr 2018 10:14:57 AEST ]]> Reducing astrocytic scarring after traumatic brain injury with a multifaceted anti-inflammatory hydrogel system https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33374 Tue 23 Oct 2018 13:32:38 AEDT ]]> The gut-brain axis in neuropsychopathology https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37534 Thu 04 Feb 2021 16:22:20 AEDT ]]> Model perturbations of glial synaptomodulatory and immune functions https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:36432 Sun 03 May 2020 16:20:21 AEST ]]> Localization of NK1 and NK3 receptors in guinea-pig brain https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1086 Sat 24 Mar 2018 08:32:09 AEDT ]]> The anabolic androgenic steroid, nandrolone decanoate, increases the density of Fos-like immunoreactive neurons in limbic regions of guinea-pig brain https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1382 Sat 24 Mar 2018 08:28:18 AEDT ]]> Effect of subchronic administration of tachykinin antagonists on response of guinea-pigs to mild and severe stress https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12344 Sat 24 Mar 2018 08:18:30 AEDT ]]> Central nervous system opiate and 5-hydroxytryptamine influences on baroreflex control of the coronary circulation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12702 Sat 24 Mar 2018 08:18:24 AEDT ]]> Role of central 5-hydroxytryptamine nerves in tonic, thermal and arterial chemoreflex control of ear vessel sympathetic innervation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12890 Sat 24 Mar 2018 08:17:13 AEDT ]]> Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18970 Sat 24 Mar 2018 07:58:53 AEDT ]]> Childhood and parental diagnostic radiological procedures and risk of childhood brain tumors https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20890 Sat 24 Mar 2018 07:57:57 AEDT ]]> Reactive gliosis in the pathogenesis of CNS diseases https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27924 Sat 24 Mar 2018 07:36:08 AEDT ]]> The effect of Schizandrol A-induced DNA methylation on SH-SY5YAB 1-40 altered neuronal cell line: a potential use in Alzheimers disease https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26413 1-40 (5 μmol/L) protein is considered to be a model of AD. Hence the aim of this study was to examine the influence of Schizandrol A, a plant extract, on DNA methylation in SH-SY5Y cells exposed to Aβ1-40. Aβ1-40 were incubated with varying concentrations of Sehizandrol A to a final concentration of 1 (low), 3 (intermediate) or 9 μg/ml (high). Exposure of SH-SY5Y with Aβ1-40 reduced viability, and altered cellular morphology and mRNA expression of DNA methyltransferase (DNMT3A) and DNMT3B. Treatment with 1 or 3 μg/ml Sehizandrol A resulted in normal cell morphology as well as elevated cell number, enhanced viability, and increased mRNA expression of DNMT3A and DNMT3B compared to saline. However, an increase in Sehizandrol A to 9 μg/ml produced a fall in cell viability, as well as a decrease in mRNA DNMT3A and DNMT3B expression to control levels. Data demonstrated that Schizandrol A at 1 or 3 μg/ml improved cell morphological appearance and viability of Aβ1-40 injured SH-SY5Y cells by an enhanced DNA methylation pathway.]]> Sat 24 Mar 2018 07:27:56 AEDT ]]> Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27576 Sat 24 Mar 2018 07:23:42 AEDT ]]> Steroid hormone mediated regulation of corticotropin-releasing hormone gene expression https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:3173 Sat 24 Mar 2018 07:18:13 AEDT ]]> Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44512 Fri 14 Oct 2022 09:11:36 AEDT ]]> Next Directions in the Neuroscience of Cancers Arising outside the CNS https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55248 Fri 03 May 2024 09:04:54 AEST ]]>